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Physician
Prescribed
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FDA Approved
Medication
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Delivered to
Your Door
Tadalafil is a PDE5 inhibitor that supports healthy blood flow by enhancing nitric oxide signaling throughout the vascular system. Taken daily at a low dose, it provides steady support for erectile function, exercise recovery, and overall vascular performance — no timing required.
Daily 5mg dosing — works continuously, not on-demand
FDA-approved medication prescribed by a licensed physician
Supports erectile function, exercise recovery, and vascular health
Discreet delivery, ongoing clinical monitoring
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It’s not in your head. After 30, nitric oxide production declines. Blood vessels lose compliance. The downstream effects show up everywhere — from the bedroom to the squat rack to your ability to stay sharp under pressure.
Tadalafil is a PDE5 inhibitor. It works by enhancing nitric oxide signaling, which relaxes smooth muscle tissue throughout the vascular system. The result is improved blood flow not just when you need it, but all day, every day. This isn’t a band-aid. It’s vascular support at the mechanism level.
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Baseline → Post-Treatment +10.4 points improvement in erectile function domain scores over 12 months of daily 5mg tadalafil 2-year open-label extension study, N=238. Porst et al., J Sex Med, 2008.
Placebo vs. Tadalafil 5mg
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23.6%
Improvement
in successful intercourse attempts vs. placebo
At 2 years of daily use:
95.7%
of patients reported
improved erections (GAQ1) 92.1% reported ability to have successful intercourse (GAQ2)
*Integrated analysis of 6 RCTs, N=1,913. Porst et al., Eur Urol, 2012. * Long-term open-label extension study. Porst et al., J Sex Med, 2008. All data from published, peer-reviewed randomized controlled trials or open-label extensions. No proprietary or unverified claims.
Tadalafil inhibits phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic GMP (cGMP) in smooth muscle tissue. By maintaining higher cGMP levels, tadalafil promotes relaxation of vascular smooth muscle — improving blood flow throughout the body. Unlike on-demand dosing, daily 5mg tadalafil maintains steady-state plasma concentration. That means consistent vascular support without timing a pill around activity.
Erectile Function
Daily dosing has been shown to significantly improve erectile function scores vs. placebo across multiple 12-week RCTs, with benefits sustained through 2 years of use.
Vascular Health
Tadalafil promotes nitric oxide-mediated vasodilation, supporting healthy endothelial function and blood vessel compliance.
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Long-Term Tolerability
Meta-analysis of 6 RCTs (N=1,596) confirmed daily 5mg tadalafil was well-tolerated over 6+ months, with no clinically significant changes in laboratory values, vital signs, or ECG readings.
of men aged 40–70 experience some degree of erectile difficulty
Massachusetts Male Aging Study
half-life of tadalafil the longest of any
PDE5 inhibitor
*FDA prescribing information
of men with severe ED achieved clinically meaningful
improvement on 5mg daily
*Integrated analysis, 6 RCTs, Eur Urol 2012
95%+ of prediabetic patients reverted to normal glucose levels.* Total weight loss reached 25.3% in extended tirzepatide treatment (88 weeks).** 89.5% of patients kept 80%+ of their weight off when staying on tirzepatide.** Significant improvements in blood pressure, triglycerides, HbA1c, and waist circumference across all dose groups.
* Jastreboff AM, et al. N Engl J Med. 2022;387(3):205–216. (SURMOUNT-1, tirzepatide) * Aronne LJ, et al. Continued Treatment
With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: SURMOUNT-4. JAMA. 2024;331(1):38–48
Concierge-level care from home — physician-guided, evidence-based, built around you.
Step 1
Test From Home
We ship a comprehensive blood panel straight to your door. Collect your sample in minutes — no clinic visit, no appointment, no hassle. Ship it back in the prepaid mailer and your results go directly to your physician.
Step 2
Meet Your Doctor
A licensed physician personally reviews your full panel and meets with you to discuss what your numbers mean, what’s working, and what isn’t. No rushed 5-minute appointments. No generic advice.
Step 3
Get Your Plan
Based on your bloodwork and consultation, your physician builds a personalized protocol whether that’s a prescription, lifestyle recommendations, or ongoing monitoring. Your treatment ships to your door, often within days.
Physician-led. Evidence-based. Built around you.
All treatments require a physician evaluation and prescription. Not available in all states. Individual results may vary.
Everything you’d expect from a concierge doctor, without the waiting room,
the referral chain or the $500 office visit.
Physician personally reviews your full panel
Personalized dosing & monitoring
Ongoing physician access
Daily dosing protocols
Discreet home delivery
Comprehensive health approach
Transparent pricing
Evidence-based protocols
Relm
Traditional Clinics
Varies — often one- size-fits-all
Office visits only
Sometimes offered
Pharmacy pickup
Siloed treatment
Insurance- dependent
Varies by provider
Traditional Clinics
Rarely — on- demand focus
Often hidden fees
Have another question? Please contact our team!
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